Agreed that more studies are required. https://pubmed.ncbi.nlm.nih.gov/25705824/
This and some others studies correlate a 40% reduction in all cause mortality (that is, 40% reduction in risk of dying from anything) with sauna use. Even if the correlation is proven to be weak, still seems worth it to get a shvitz whenever you can.
From general systems biology perspective everything that moves body metabolism away from it's normal state for short time seems to give benefits, exercise, cold, heat, hunger, ... allostatic load that is not chronic is generally good.
My hot take hopeful guess is that heat shock causes upregulation of protein degradation / chaperone activity, thereby disrupting protein aggregation involved in AD, PD, et all. One can hope
Agreed that more studies are required. https://pubmed.ncbi.nlm.nih.gov/25705824/ This and some others studies correlate a 40% reduction in all cause mortality (that is, 40% reduction in risk of dying from anything) with sauna use. Even if the correlation is proven to be weak, still seems worth it to get a shvitz whenever you can.
I'm a Finn so I'm biased.
From general systems biology perspective everything that moves body metabolism away from it's normal state for short time seems to give benefits, exercise, cold, heat, hunger, ... allostatic load that is not chronic is generally good.
My hot take hopeful guess is that heat shock causes upregulation of protein degradation / chaperone activity, thereby disrupting protein aggregation involved in AD, PD, et all. One can hope
https://archive.md/aRRVl